BioLegacy transforms tissue into definitive, quantitative data, providing a critical link between your in vivo study and its mechanistic and toxicological conclusions. Our full-service histology and pathology laboratory is designed to deliver rapid, high-quality tissue processing, sectioning, and staining to support both regulated GLP and exploratory research programs. By integrating our deep expertise in a wide array of routine and advanced staining techniques with state-of-the-art digital pathology and image analysis, we provide objective, reproducible data packages that clearly elucidate your therapeutic’s efficacy and safety profile at the cellular level.
The foundation of histological evaluation is the preparation of high-quality tissue specimens. Our core histology laboratory provides a complete service for both paraffin-embedded (FFPE) and frozen (OCT) tissues. We combine state-of-the-art automation with the precision of our highly experienced histotechnologists to ensure the consistent generation of tissue sections for any downstream application, from routine analysis to advanced molecular pathology.
To elucidate your therapeutic’s mechanism of action and confirm target engagement at the cellular level, we offer a suite of advanced molecular pathology services. BioLegacy provides development, optimization, and validation of custom staining assays to visualize and quantify key biomarkers directly in tissue. Used to assess drug efficacy and safety, our molecular pathology services provide critical insights into the biological response within the precise tissue microenvironment.
BioLegacy’s histology workflow integrates state-of-the-art digital pathology. Leveraging powerful, unbiased image analysis we precisely quantify a wide range of pathological and biomarker endpoints. This rigorous, data-driven approach removes subjectivity, increases statistical power, and delivers the objective, reproducible results required for confident decision-making and IND submissions.
BioLegacy provides secure, GLP-compliant archiving for all physical specimens, including wet tissues, blocks, and slides, in environmentally-monitored facilities to meet global regulatory requirements (including FDA § 58.195). Optional digital slide archiving provides you with instant, secure access to your virtual slides for future review, re-analysis, or remote collaboration, safeguarding your valuable data assets for the lifetime of your program without concern of sample degradation or loss of signal.
BioLegacy’s capacity and flexibility get you to IND sooner. Work with us!