# BioLegacy Research
> BioLegacy Research is a San Diego preclinical CRO (in vitro and in vivo) supporting discovery through IND/IDE. Hundreds of animal models across a dozen therapeutic areas; species from mice to non-human primates; GLP toxicology; custom assays and novel model development; medical device surgical testing. AAALAC-standard ~18,000 sq ft vivarium. A PharmaLegacy company (formerly BTS Research).

Human site: https://biolegacyresearch.com — Markdown mirrors append .md to the page path. PDF text mirrors append .md to the PDF URL. Lab: 6042 Cornerstone Court W, Suite E, San Diego, CA 92121. Phone (858) 605-5882. Toll free (866) 599-3019. Email info@biolegacyresearch.com. Hours 9am–6pm US Pacific.

## Start here

- [Home](https://biolegacyresearch.com/index.md): San Diego preclinical CRO: in vitro screening through GLP IND-enabling studies, mice to NHPs, devices.
- [About BioLegacy](https://biolegacyresearch.com/about-biolegacy.md): History since 2001 (formerly BTS Research), facilities, values; PharmaLegacy company.
- [Services](https://biolegacyresearch.com/services.md): Toxicology, pharmacology, model development, devices, in vitro, custom assays, vivarium rental, histology.
- [Therapeutic Areas](https://biolegacyresearch.com/preclinical-therapeutic-areas.md): Disease-area index: oncology, immunology, CNS, CV, metabolism, and more.
- [Species](https://biolegacyresearch.com/biolegacy-species.md): NHP, dog, minipig, rabbit, rodent, sheep, and other research species.
- [Capabilities](https://biolegacyresearch.com/biolegacy-capabilities.md): GLP/IND-enabling studies, housing, and bioanalytical platforms.
- [News](https://biolegacyresearch.com/news.md): FDA/USDA inspections, facility expansion, and company name change.
- [Contact](https://biolegacyresearch.com/contact.md): San Diego address, phone, fax, and info@biolegacyresearch.com.
- [Request a Quote](https://biolegacyresearch.com/request-a-quote.md): Study inquiry form.

## Services

- [Toxicology](https://biolegacyresearch.com/service/toxicology-ind-submission.md): Discovery through GLP IND-ready tox and safety pharmacology.
- [Pharmacology](https://biolegacyresearch.com/service/pharmacology.md): PK/PD in relevant models; GLP and non-GLP; bioanalysis.
- [Animal Model Development](https://biolegacyresearch.com/service/animal-model-development.md): Transgenic, xenograft, chemical or surgical models matched to MoA.
- [Medical Device Testing](https://biolegacyresearch.com/service/medical-device-testing.md): Implantable device surgery and IDE-oriented device studies.
- [In Vitro Screening](https://biolegacyresearch.com/service/in-vitro-screening.md): Cell-based assays, biomarkers, target engagement.
- [Custom Assay Development](https://biolegacyresearch.com/service/custom-assay-development.md): Bespoke in vitro assays for MoA, efficacy, or toxicity.
- [Vivarium Rental](https://biolegacyresearch.com/service/vivarium-rental.md): AAALAC-standard ~18,000 sq ft vivarium; small and large animals.
- [Histology](https://biolegacyresearch.com/service/histology.md): H&E through IHC; efficacy, engagement, and safety histology.

## Therapeutic areas

- [Oncology](https://biolegacyresearch.com/therapeutic-areas/oncology.md): Oncology models.
- [Immunology & Inflammation](https://biolegacyresearch.com/therapeutic-areas/immunology-inflammation.md): Immunology and inflammation models.
- [Neurology / CNS](https://biolegacyresearch.com/therapeutic-areas/neurology-cns.md): CNS and neurology models.
- [Cardiovascular](https://biolegacyresearch.com/therapeutic-areas/cardiovascular-studies.md): Cardiovascular models.
- [Metabolism](https://biolegacyresearch.com/therapeutic-areas/metabolism-studies.md): Metabolic disease models.
- [Gastroenterology](https://biolegacyresearch.com/therapeutic-areas/gastroenterology-studies.md): GI models.
- [Hepatology](https://biolegacyresearch.com/therapeutic-areas/hepatology-studies.md): Liver disease models.
- [Pulmonology](https://biolegacyresearch.com/therapeutic-areas/pulmonology-studies.md): Lung disease models.
- [Infectious Diseases & Sepsis](https://biolegacyresearch.com/therapeutic-areas/infectious-diseases-sepsis.md): Infectious disease and sepsis models.
- [Musculoskeletal](https://biolegacyresearch.com/therapeutic-areas/musculoskeletal-studies.md): Musculoskeletal models.
- [Nephrology & Urology](https://biolegacyresearch.com/therapeutic-areas/nephrology-urology-studies.md): Kidney and urology models.
- [Dermatology & Wound Healing](https://biolegacyresearch.com/therapeutic-areas/dermatology-wound-healing.md): Dermatology and wound-healing models.

## Species

- [Non-human Primates](https://biolegacyresearch.com/species/non-human-primates.md): NHP capacity and studies.
- [Dogs](https://biolegacyresearch.com/species/canine-studies.md): Canine studies.
- [Minipigs / Pigs](https://biolegacyresearch.com/species/minipigs-pigs.md): Swine studies.
- [Rabbits](https://biolegacyresearch.com/species/rabbit-studies.md): Rabbit studies.
- [Mice](https://biolegacyresearch.com/species/mouse-studies.md): Mouse studies.
- [Rats](https://biolegacyresearch.com/species/rat-studies.md): Rat studies.
- [Sheep](https://biolegacyresearch.com/species/sheep.md): Ovine studies.
- [Guinea Pigs](https://biolegacyresearch.com/species/guinea-pig-studies.md): Guinea pig studies.
- [Hamsters](https://biolegacyresearch.com/species/hamster-studies.md): Hamster studies.
- [Other Species](https://biolegacyresearch.com/species/other-species.md): Additional research species.

## Capabilities

- [GLP / IND-Enabling Studies](https://biolegacyresearch.com/capabilities/glp-ind-enabling-studies.md): GLP packages for IND/IDE support.
- [Small and Large Animal Housing](https://biolegacyresearch.com/capabilities/small-and-large-animal-housing.md): Housing for rodents through large animals and NHPs.
- [Bioanalytical Platforms](https://biolegacyresearch.com/capabilities/bioanalytical-platforms.md): Bioanalysis supporting PK/PD and in vitro work.

## Company

- [Careers](https://biolegacyresearch.com/careers.md): Open positions.

## Documents

- [Meier-Davis 2015 International Journal of Toxicology](https://biolegacyresearch.com/wp-content/uploads/2015/10/MeierDavis-2015-Intl-J-Tox-34-11.pdf.md): Public cynomolgus monkey vaginal safety paper (extractable text).
- [BTS USDA document](https://biolegacyresearch.com/wp-content/uploads/2017/12/BTS-USDA.pdf.md): Legacy BTS USDA PDF (image-only stub).

## Articles

- [Acute and Chronic Rodent Models of Liver Fibrosis](https://biolegacyresearch.com/acute-chronic-rodent-models-liver-fibrosis.md)
- [Advanced NHP Research Capabilities: Molecular Imaging](https://biolegacyresearch.com/advanced-nhp-research-capabilities-molecular-imaging.md)
- [Apricus Biosciences Sells Bio-Quant CRO Subsidiary to BioTox Sciences](https://biolegacyresearch.com/apricus-biosciences-sells-bio-quant-cro-subsidiary-biotox-sciences.md)
- [BIO-QUANT announces the expansion of its research animal diagnostic services to cover all nine species](https://biolegacyresearch.com/bio-quant-announces-expansion-research-animal-diagnostic-services-cover-nine-species.md)
- [BIO-QUANT credited in TRIUS POSTER](https://biolegacyresearch.com/bio-quant-credited-trius-poster.md)
- [BIO-QUANT credited in XOMA POSTER](https://biolegacyresearch.com/bio-quant-credited-xoma-poster.md)
- [BioLegacy Research Passes USDA Inspection with Zero Findings](https://biolegacyresearch.com/biolegacy-research-passes-usda-inspection-with-zero-findings.md)
- [BioLegacy Research Successfully Passes 2025 FDA Inspection](https://biolegacyresearch.com/biolegacy-research-successfully-passes-2025-fda-inspection.md)
- [BioQuant & BioTox Sciences is Now BTS Research](https://biolegacyresearch.com/bioquant-biotox-sciences-is-now-bts-research.md)
- [BioTox Sciences – Introducing the New Website for BioTox Sciences and Bio-Quant](https://biolegacyresearch.com/biotox-sciences-introducing-new-website-biotox-sciences-bio-quant.md)
- [BioTox Sciences – San Diego’s Best CRO Housing-Vivarium](https://biolegacyresearch.com/biotox-sciences-san-diegos-best-cro-housing-vivarium.md)
- [BioTox Sciences (BTS) Deploys eStudy™ Hosted Solution for Management of GLP & Non-GLP Preclinical Studies](https://biolegacyresearch.com/biotox-sciences-bts-deploys-estudy-hosted-solution-management-glp-non-glp-preclinical-studies.md)
- [BioTox Sciences Attends The 2013 SOT](https://biolegacyresearch.com/biotox-sciences-attends-2013-sot.md)
- [BioTox Sciences Attends The 2014 SOT](https://biolegacyresearch.com/biotox-sciences-attends-2014-sot.md)
- [BioTox Sciences Attends the American Association for Cancer Research Annual Meeting](https://biolegacyresearch.com/biotox-sciences-attends-american-association-cancer-research-annual-meeting.md)
- [BioTox Sciences Attends the American Association for Cancer Research Annual Meeting](https://biolegacyresearch.com/biotox-sciences-attends-american-association-cancer-research-annual-meeting-2.md)
- [BioTox Sciences Attends The American Association for Cancer Research Annual Meeting 2014](https://biolegacyresearch.com/biotox-sciences-attends-american-association-cancer-research-annual-meeting-2014.md)
- [BioTox Sciences Attends the American Association of Pharmaceutical Scientist Annual Meeting and Exposition](https://biolegacyresearch.com/biotox-sciences-attends-american-association-pharmaceutical-scientist-annual-meeting-exposition-2.md)
- [BioTox Sciences Attends the American Association of Pharmaceutical Scientist Annual Meeting and Exposition](https://biolegacyresearch.com/biotox-sciences-attends-american-association-pharmaceutical-scientist-annual-meeting-exposition.md)
- [BioTox Sciences Attends the American College of Toxicology Annual Meeting](https://biolegacyresearch.com/biotox-sciences-attends-american-college-toxicology-annual-meeting-2.md)
- [BioTox Sciences Attends the American College of Toxicology Annual Meeting](https://biolegacyresearch.com/biotox-sciences-attends-american-college-toxicology-annual-meeting.md)
- [BioTox Sciences Attends the Drug Delivery and Formulation America Summit](https://biolegacyresearch.com/biotox-sciences-attends-drug-delivery-formulation-america-summit.md)
- [BioTox Sciences Attends The Drug Discovery Chemistry Meeting](https://biolegacyresearch.com/biotox-sciences-attends-drug-discovery-chemistry-meeting.md)
- [BioTox Sciences Attends the International Society for Stem Cell Research Annual Meeting](https://biolegacyresearch.com/biotox-sciences-attends-international-society-stem-cell-research-annual-meeting.md)
- [BioTox Sciences Attends the Society of Toxicology: Annual Meeting and Tox Expo](https://biolegacyresearch.com/biotox-sciences-attends-society-toxicology-annual-meeting-tox-expo.md)
- [BioTox Sciences Attends the Society of Toxicology: Annual Meeting and Toxicology Expo](https://biolegacyresearch.com/biotox-sciences-attends-society-toxicology-annual-meeting-toxicology-expo.md)
- [BioTox Sciences Expedient and Reliable Screening Support](https://biolegacyresearch.com/biotox-sciences-expedient-reliable-screening-support.md)
- [BioTox Sciences FDA Audit News](https://biolegacyresearch.com/biotox-sciences-fda-audit-news.md)
- [BioTox Sciences Merger & Acquisition Update](https://biolegacyresearch.com/biotox-sciences-merger-acquisition-update.md)
- [BioTox Sciences, Your Partner In Drug Development](https://biolegacyresearch.com/biotox-sciences-partner-drug-development.md)
- [BTS Research Addresses FDA Warning Letter Satisfactorily](https://biolegacyresearch.com/ts-research-addresses-fda-warning-letter-satisfactorily.md)
- [BTS Research Appoints Mark Crane as Vice President, Business Development](https://biolegacyresearch.com/bts-research-appoints-mark-crane-as-vice-president-business-development.md)
- [BTS Research Appoints VP of Toxicology to Oversee Sponsors’ Preclinical Tox Programs](https://biolegacyresearch.com/bts-research-appoints-vp-toxicology-oversee-sponsors-preclinical-tox-programs.md)
- [BTS Research Attends The 2014 AAPS](https://biolegacyresearch.com/bts-research-attends-the-2014-aaps.md)
- [BTS Research Attends The 2014 AAPS National Biotechnology Conference](https://biolegacyresearch.com/bts-research-attends-the-2014-aaps-national-biotechnology-conference.md)
- [BTS Research Attends The 2014 ACT](https://biolegacyresearch.com/bts-research-attends-the-2014-act.md)
- [BTS Research Completes Corrections of FDA 483 Observations](https://biolegacyresearch.com/bts-research-completes-corrections-of-fda-483-observations.md)
- [BTS Research Earns Full AAALAC Accreditation Renewal](https://biolegacyresearch.com/bts-research-earns-full-aaalac-accreditation-renewal.md)
- [BTS Research Passed USDA Inspection](https://biolegacyresearch.com/bts-research-passed-usda-inspection.md)
- [BTS Research Passed USDA Inspection 2018](https://biolegacyresearch.com/bts-research-passed-usda-inspection-2018.md)
- [BTS Research Passes an FDA Bioresearch Monitoring Program Inspection for GLP Rat and Dog Toxicity Studies](https://biolegacyresearch.com/bts-research-passes-an-fda-bioresearch-monitoring-program-inspection-for-glp-rat-and-dog-toxicity-studies.md)
- [BTS Research Successfully Completes USDA Inspection with Zero Findings](https://biolegacyresearch.com/bts-research-successfully-completes-usda-inspection-with-zero-findings.md)
- [BTS Research To Attend AAPS 2016 Denver Colorado](https://biolegacyresearch.com/bts-research-attend-aaps-2016-denver-colorado.md)
- [BTS Research’s, Sam Abunadi President & CEO, urges the FDA to require “Clinical Trials” for Cannabis dose determination as a scheduled substance with not yet classified strands](https://biolegacyresearch.com/bts-researchs-sam-abunadi-president-ceo-urges-the-fda-to-require-clinical-trials-for-cannabis-dose-determination-as-a-scheduled-substance-with-not-yet-classified-strands.md)
- [COVID-19 Response](https://biolegacyresearch.com/covid-19-response.md)
- [HMGB1 Studies in wound healing. SOURCE: Bio-Quant, Inc. HMGB1 Studies in wound healing.](https://biolegacyresearch.com/hmgb1-studies-wound-healing-source-bio-quant-inc-hmgb1-studies-wound-healing.md)
- [International Journal of Toxicology](https://biolegacyresearch.com/international-journal.md)
- [Official Company Name Change Announcement](https://biolegacyresearch.com/official-company-name-change-announcement.md)
- [Pharma Companies in San Diego](https://biolegacyresearch.com/pharma-companies-in-san-diego.md)
- [PharmaLegacy acquires preclinical CRO BTS Research,](https://biolegacyresearch.com/pharmalegacy-acquires-preclinical-cro-bts-research.md)
- [PharmaLegacy Research LLC, dba. BTS Research Announces Expansion of their Headquarters & In Vitro Labs in their New San Diego Facility](https://biolegacyresearch.com/bts-research-expansion-in-vitro-labs-new-san-diego-facility.md)
- [Preclinical CRO](https://biolegacyresearch.com/preclinical-cro.md)